ruleID organism gene nodeID refseq accession GenBank accession HMM accession ARO accession mutation variation type context drug drug class phenotype clinical category breakpoint breakpoint standard PMID evidence code evidence grade evidence limitations rule curation note ACI0001 s__Acinetobacter baumannii blaOXA-23_fam blaOXA-23_fam - - NF000266.2 ARO:3007710 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 10602749 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "bla0XA-23 is a core gene in Acinetobacter radioresistens, acquired in all other organisms." ACI0002 s__Acinetobacter baumannii blaOXA-23 blaOXA-23 WP_001046004.1 - - ARO:3001418 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 10602749 ECO:0001103 natural variation mutant evidence strong "blaOXA-23 is a core gene in Acinetobacter radioresistens and does not confer carbapenem resistance unless there is an IS element upstream that leads to overexpression. blaOXA-23 can be acquired by other Acinetobacter species and is associated with ISAba1, and carbapenem resistance." ACI0003 s__Acinetobacter baumannii blaOXA-27 blaOXA-27 WP_063862443.1 - - ARO:3001422 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 11158758 ECO:0001103 natural variation mutant evidence strong "bla0XA-23 is a core gene in Acinetobacter radioresistens, acquired in all other organisms." ACI0004 s__Acinetobacter baumannii blaOXA-49 blaOXA-49 WP_063864111.1 - - ARO:3001671 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 22842601 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected No specific MIC is described in the associated paper. ACI0005 s__Acinetobacter baumannii blaOXA-146 blaOXA-146 WP_063861044.1 - - ARO:3001779 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 23877677 ECO:0001103 natural variation mutant evidence strong lacks evidence of the degree to which MIC is affected ACI0006 s__Acinetobacter baumannii blaOXA-165 blaOXA-165 WP_063861123.1 - - ARO:3001465 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0007 s__Acinetobacter baumannii blaOXA-166 blaOXA-166 WP_063861129.1 - - ARO:3001466 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0008 s__Acinetobacter baumannii blaOXA-167 blaOXA-167 WP_063861133.1 - - ARO:3001467 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0009 s__Acinetobacter baumannii blaOXA-168 blaOXA-168 WP_063861136.1 - - ARO:3001468 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0010 s__Acinetobacter baumannii blaOXA-169 blaOXA-169 WP_063861140.1 - - ARO:3001469 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0011 s__Acinetobacter baumannii blaOXA-170 blaOXA-170 WP_063861151.1 - - ARO:3001470 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0012 s__Acinetobacter baumannii blaOXA-171 blaOXA-171 WP_063861157.1 - - ARO:3001471 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0013 s__Acinetobacter baumannii blaOXA-225 blaOXA-225 WP_063861820.1 - - ARO:3001493 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0014 s__Acinetobacter baumannii blaOXA-239 blaOXA-239 WP_063862190.1 - - ARO:3001498 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0015 s__Acinetobacter baumannii blaOXA-366 blaOXA-366 WP_063862736.1 - - ARO:3001553 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0016 s__Acinetobacter baumannii blaOXA-398 blaOXA-398 WP_063862757.1 - - ARO:3001584 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0017 s__Acinetobacter baumannii blaOXA-422 blaOXA-422 WP_063862828.1 - - ARO:3003160 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0018 s__Acinetobacter baumannii blaOXA-423 blaOXA-423 WP_063862833.1 - - ARO:3003161 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0019 s__Acinetobacter baumannii blaOXA-435 blaOXA-435 WP_063864078.1 - - ARO:3003162 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0020 s__Acinetobacter baumannii blaOXA-440 blaOXA-440 WP_063864082.1 - - ARO:3003596 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0021 s__Acinetobacter baumannii blaOXA-482 blaOXA-482 WP_063864108.1 - - ARO:3003639 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0022 s__Acinetobacter baumannii blaOXA-483 blaOXA-483 WP_063864109.1 - - ARO:3003640 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0023 s__Acinetobacter baumannii blaOXA-565 blaOXA-565 WP_085562421.1 - - ARO:3005789 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0024 s__Acinetobacter baumannii blaOXA-657 blaOXA-657 WP_111672907.1 - - ARO:3005872 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0025 s__Acinetobacter baumannii blaOXA-911 blaOXA-911 WP_168247884.1 - - ARO:3006098 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0026 s__Acinetobacter baumannii blaOXA-1216 blaOXA-1216 WP_311033317.1 - - - - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0027 s__Acinetobacter baumannii blaOXA-1223 blaOXA-1223 WP_318245554.1 - - - - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0028 s__Acinetobacter baumannii blaOXA-1241 blaOXA-1241 WP_367187965.1 - - - - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0029 s__Acinetobacter baumannii blaOXA-24_fam blaOXA-24_fam - - NF000434.2 ARO:3007711 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0030 s__Acinetobacter baumannii blaOXA-24 blaOXA-24 WP_012754353.1 - - ARO:3001419 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) "12499201, 10817708, 21041501" ECO:0001103 natural variation mutant evidence strong MIC 256 mg/L (imipenem) ; MIC 256 mg/L (meropenem) ACI0031 s__Acinetobacter baumannii blaOXA-72 blaOXA-72 WP_000713530.1 - - ARO:3001705 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) "17846127, 21041501" ECO:0001103 natural variation mutant evidence strong MIC 16 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0032 s__Acinetobacter baumannii blaOXA-58_fam blaOXA-58_fam - - NF000500.2 ARO:3007728 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0033 s__Acinetobacter baumannii blaOXA-58 blaOXA-58 WP_002002480.1 - - ARO:3001611 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 15616297 ECO:0001103 natural variation mutant evidence strong MIC 32 mg/L (imipenem) ; MIC >64 mg/L (meropenem) ACI0034 s__Acinetobacter baumannii blaOXA-96 blaOXA-96 WP_063864543.1 - - ARO:3001631 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 17284537 ECO:0001103 natural variation mutant evidence strong MIC 16 mg/L (imipenem) ACI0035 s__Acinetobacter baumannii blaOXA-97 blaOXA-97 WP_063864544.1 - - ARO:3001647 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 18299404 ECO:0001103 natural variation mutant evidence strong MIC 32 mg/L (imipenem) ; MIC 16 mg/L (meropenem) ACI0036 s__Acinetobacter baumannii blaOXA-164 blaOXA-164 WP_063861121.1 - - ARO:3001662 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 20921306 ECO:0001103 natural variation mutant evidence strong MIC 8...>=16 mg/L (imipenem) ; MIC 2...8 mg/L (meropenem) (Vitek2) ; MIC 32 mg/L (imipenem) ; MIC 8...32 mg/L (meropenem) (Etest) ACI0037 s__Acinetobacter baumannii blaOXA-235 blaOXA-235 WP_000854009.1 - - ARO:3001676 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (imipenem) ; MIC >=16 mg/L (meropenem) ACI0038 s__Acinetobacter baumannii blaOXA-236 blaOXA-236 WP_063862170.1 - - ARO:3001677 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (imipenem) ; MIC >=16 mg/L (meropenem) ACI0039 s__Acinetobacter baumannii blaOXA-237 blaOXA-237 WP_000854010.1 - - ARO:3001678 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (imipenem) ; MIC >=16 mg/L (meropenem) ACI0041 s__Acinetobacter baumannii blaOXA-143_fam blaOXA-143_fam - - NF000464.2 ARO:3007701 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0042 s__Acinetobacter baumannii blaOXA-143 blaOXA-143 WP_063861042.1 - - ARO:3001654 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 19770279 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0043 s__Acinetobacter baumannii blaOXA-182 blaOXA-182 WP_063861266.1 - - ARO:3001709 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 20884158 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected Phenotype of this gene in Acinetobacter baumannii inferred from the other members of the family. ACI0044 s__Acinetobacter baumannii blaOXA-231 blaOXA-231 WP_063862128.1 - - ARO:3001670 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) "22736746 24566181" ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0045 s__Acinetobacter baumannii blaOXA-253 blaOXA-253 WP_032495764.1 - - ARO:3001689 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 24566181 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0046 s__Acinetobacter baumannii blaNDM blaNDM - - NF000259.2 ARO:3000057 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected Phenotype of this gene family inferred from MICs of several members. ACI0047 s__Acinetobacter baumannii blaNDM-1 blaNDM-1 WP_004201164.1 - - ARO:3000589 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 21693460 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0048 s__Acinetobacter baumannii blaNDM-2 blaNDM-2 WP_063860860.1 - - ARO:3000590 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 21427107 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0049 s__Acinetobacter baumannii blaNDM-6 blaNDM-6 WP_032495384.1 - - ARO:3002356 - Gene presence detected acquired - carbapenem nonwildtype R not applicable EUCAST v14.0 (2024) 33240245 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0050 s__Acinetobacter baumannii blaOXA-23_fam blaOXA-23_fam - - NF000266.2 ARO:3007710 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 10602749 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "bla0XA-23 is a core gene in Acinetobacter radioresistens, acquired in all other organisms." ACI0051 s__Acinetobacter baumannii blaOXA-23_fam blaOXA-23_fam - - NF000266.2 ARO:3007710 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 10602749 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "bla0XA-23 is a core gene in Acinetobacter radioresistens, acquired in all other organisms." ACI0052 s__Acinetobacter baumannii blaOXA-23 blaOXA-23 WP_001046004.1 - - ARO:3001418 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 10602749 ECO:0001103 natural variation mutant evidence strong "blaOXA-23 is a core gene in Acinetobacter radioresistens and does not confer carbapenem resistance unless there is an IS element upstream that leads to overexpression. blaOXA-23 can be acquired by other Acinetobacter species and is associated with ISAba1, and carbapenem resistance." ACI0053 s__Acinetobacter baumannii blaOXA-23 blaOXA-23 WP_001046004.1 - - ARO:3001418 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 10602749 ECO:0001103 natural variation mutant evidence strong "blaOXA-23 is a core gene in Acinetobacter radioresistens and does not confer carbapenem resistance unless there is an IS element upstream that leads to overexpression. blaOXA-23 can be acquired by other Acinetobacter species and is associated with ISAba1, and carbapenem resistance." ACI0054 s__Acinetobacter baumannii blaOXA-27 blaOXA-27 WP_063862443.1 - - ARO:3001422 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 11158758 ECO:0001103 natural variation mutant evidence strong "bla0XA-23 is a core gene in Acinetobacter radioresistens, acquired in all other organisms." ACI0055 s__Acinetobacter baumannii blaOXA-27 blaOXA-27 WP_063862443.1 - - ARO:3001422 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 11158758 ECO:0001103 natural variation mutant evidence strong "bla0XA-23 is a core gene in Acinetobacter radioresistens, acquired in all other organisms." ACI0056 s__Acinetobacter baumannii blaOXA-49 blaOXA-49 WP_063864111.1 - - ARO:3001671 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 22842601 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected No specific MIC is described in the associated paper. ACI0057 s__Acinetobacter baumannii blaOXA-49 blaOXA-49 WP_063864111.1 - - ARO:3001671 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 22842601 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected No specific MIC is described in the associated paper. ACI0058 s__Acinetobacter baumannii blaOXA-146 blaOXA-146 WP_063861044.1 - - ARO:3001779 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 23877677 ECO:0001103 natural variation mutant evidence strong lacks evidence of the degree to which MIC is affected ACI0059 s__Acinetobacter baumannii blaOXA-146 blaOXA-146 WP_063861044.1 - - ARO:3001779 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 23877677 ECO:0001103 natural variation mutant evidence strong lacks evidence of the degree to which MIC is affected ACI0060 s__Acinetobacter baumannii blaOXA-165 blaOXA-165 WP_063861123.1 - - ARO:3001465 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0061 s__Acinetobacter baumannii blaOXA-165 blaOXA-165 WP_063861123.1 - - ARO:3001465 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0062 s__Acinetobacter baumannii blaOXA-166 blaOXA-166 WP_063861129.1 - - ARO:3001466 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0063 s__Acinetobacter baumannii blaOXA-166 blaOXA-166 WP_063861129.1 - - ARO:3001466 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0064 s__Acinetobacter baumannii blaOXA-167 blaOXA-167 WP_063861133.1 - - ARO:3001467 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0065 s__Acinetobacter baumannii blaOXA-167 blaOXA-167 WP_063861133.1 - - ARO:3001467 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0066 s__Acinetobacter baumannii blaOXA-168 blaOXA-168 WP_063861136.1 - - ARO:3001468 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0067 s__Acinetobacter baumannii blaOXA-168 blaOXA-168 WP_063861136.1 - - ARO:3001468 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0068 s__Acinetobacter baumannii blaOXA-169 blaOXA-169 WP_063861140.1 - - ARO:3001469 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0069 s__Acinetobacter baumannii blaOXA-169 blaOXA-169 WP_063861140.1 - - ARO:3001469 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0070 s__Acinetobacter baumannii blaOXA-170 blaOXA-170 WP_063861151.1 - - ARO:3001470 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0071 s__Acinetobacter baumannii blaOXA-170 blaOXA-170 WP_063861151.1 - - ARO:3001470 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0072 s__Acinetobacter baumannii blaOXA-171 blaOXA-171 WP_063861157.1 - - ARO:3001471 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0073 s__Acinetobacter baumannii blaOXA-171 blaOXA-171 WP_063861157.1 - - ARO:3001471 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0074 s__Acinetobacter baumannii blaOXA-225 blaOXA-225 WP_063861820.1 - - ARO:3001493 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0075 s__Acinetobacter baumannii blaOXA-225 blaOXA-225 WP_063861820.1 - - ARO:3001493 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0076 s__Acinetobacter baumannii blaOXA-239 blaOXA-239 WP_063862190.1 - - ARO:3001498 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0077 s__Acinetobacter baumannii blaOXA-239 blaOXA-239 WP_063862190.1 - - ARO:3001498 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0078 s__Acinetobacter baumannii blaOXA-366 blaOXA-366 WP_063862736.1 - - ARO:3001553 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0079 s__Acinetobacter baumannii blaOXA-366 blaOXA-366 WP_063862736.1 - - ARO:3001553 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0080 s__Acinetobacter baumannii blaOXA-398 blaOXA-398 WP_063862757.1 - - ARO:3001584 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0081 s__Acinetobacter baumannii blaOXA-398 blaOXA-398 WP_063862757.1 - - ARO:3001584 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0082 s__Acinetobacter baumannii blaOXA-422 blaOXA-422 WP_063862828.1 - - ARO:3003160 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0083 s__Acinetobacter baumannii blaOXA-422 blaOXA-422 WP_063862828.1 - - ARO:3003160 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0084 s__Acinetobacter baumannii blaOXA-423 blaOXA-423 WP_063862833.1 - - ARO:3003161 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0085 s__Acinetobacter baumannii blaOXA-423 blaOXA-423 WP_063862833.1 - - ARO:3003161 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0086 s__Acinetobacter baumannii blaOXA-435 blaOXA-435 WP_063864078.1 - - ARO:3003162 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0087 s__Acinetobacter baumannii blaOXA-435 blaOXA-435 WP_063864078.1 - - ARO:3003162 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0088 s__Acinetobacter baumannii blaOXA-440 blaOXA-440 WP_063864082.1 - - ARO:3003596 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0089 s__Acinetobacter baumannii blaOXA-440 blaOXA-440 WP_063864082.1 - - ARO:3003596 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0090 s__Acinetobacter baumannii blaOXA-482 blaOXA-482 WP_063864108.1 - - ARO:3003639 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0091 s__Acinetobacter baumannii blaOXA-482 blaOXA-482 WP_063864108.1 - - ARO:3003639 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0092 s__Acinetobacter baumannii blaOXA-483 blaOXA-483 WP_063864109.1 - - ARO:3003640 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0093 s__Acinetobacter baumannii blaOXA-483 blaOXA-483 WP_063864109.1 - - ARO:3003640 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0094 s__Acinetobacter baumannii blaOXA-565 blaOXA-565 WP_085562421.1 - - ARO:3005789 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0095 s__Acinetobacter baumannii blaOXA-565 blaOXA-565 WP_085562421.1 - - ARO:3005789 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0096 s__Acinetobacter baumannii blaOXA-657 blaOXA-657 WP_111672907.1 - - ARO:3005872 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0097 s__Acinetobacter baumannii blaOXA-657 blaOXA-657 WP_111672907.1 - - ARO:3005872 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0098 s__Acinetobacter baumannii blaOXA-911 blaOXA-911 WP_168247884.1 - - ARO:3006098 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0099 s__Acinetobacter baumannii blaOXA-911 blaOXA-911 WP_168247884.1 - - ARO:3006098 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0100 s__Acinetobacter baumannii blaOXA-1216 blaOXA-1216 WP_311033317.1 - - - - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0101 s__Acinetobacter baumannii blaOXA-1216 blaOXA-1216 WP_311033317.1 - - - - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0102 s__Acinetobacter baumannii blaOXA-1223 blaOXA-1223 WP_318245554.1 - - - - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0103 s__Acinetobacter baumannii blaOXA-1223 blaOXA-1223 WP_318245554.1 - - - - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0104 s__Acinetobacter baumannii blaOXA-1241 blaOXA-1241 WP_367187965.1 - - - - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0105 s__Acinetobacter baumannii blaOXA-1241 blaOXA-1241 WP_367187965.1 - - - - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence for this allele No associated paper available specifically for this allele. Phenotype inferred from the family. ACI0106 s__Acinetobacter baumannii blaOXA-24_fam blaOXA-24_fam - - NF000434.2 ARO:3007711 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0107 s__Acinetobacter baumannii blaOXA-24_fam blaOXA-24_fam - - NF000434.2 ARO:3007711 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0108 s__Acinetobacter baumannii blaOXA-24 blaOXA-24 WP_012754353.1 - - ARO:3001419 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) "12499201, 10817708, 21041501" ECO:0001103 natural variation mutant evidence strong MIC 256 mg/L (imipenem) ; MIC 256 mg/L (meropenem) ACI0109 s__Acinetobacter baumannii blaOXA-24 blaOXA-24 WP_012754353.1 - - ARO:3001419 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) "12499201, 10817708, 21041501" ECO:0001103 natural variation mutant evidence strong MIC 256 mg/L (imipenem) ; MIC 256 mg/L (meropenem) ACI0110 s__Acinetobacter baumannii blaOXA-72 blaOXA-72 WP_000713530.1 - - ARO:3001705 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) "17846127, 21041501" ECO:0001103 natural variation mutant evidence strong MIC 16 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0111 s__Acinetobacter baumannii blaOXA-72 blaOXA-72 WP_000713530.1 - - ARO:3001705 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) "17846127, 21041501" ECO:0001103 natural variation mutant evidence strong MIC 16 mg/L (imipenem) ; MIC >32 mg/L (meropenem) ACI0112 s__Acinetobacter baumannii blaOXA-58_fam blaOXA-58_fam - - NF000500.2 ARO:3007728 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0113 s__Acinetobacter baumannii blaOXA-58_fam blaOXA-58_fam - - NF000500.2 ARO:3007728 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0114 s__Acinetobacter baumannii blaOXA-58 blaOXA-58 WP_002002480.1 - - ARO:3001611 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 15616297 ECO:0001103 natural variation mutant evidence strong MIC 32 mg/L (imipenem) ; MIC >64 mg/L (meropenem) ACI0115 s__Acinetobacter baumannii blaOXA-58 blaOXA-58 WP_002002480.1 - - ARO:3001611 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 15616297 ECO:0001103 natural variation mutant evidence strong MIC 32 mg/L (imipenem) ; MIC >64 mg/L (meropenem) ACI0116 s__Acinetobacter baumannii blaOXA-96 blaOXA-96 WP_063864543.1 - - ARO:3001631 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 17284537 ECO:0001103 natural variation mutant evidence strong MIC 16 mg/L (imipenem) ACI0117 s__Acinetobacter baumannii blaOXA-96 blaOXA-96 WP_063864543.1 - - ARO:3001631 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 17284537 ECO:0001103 natural variation mutant evidence strong MIC 16 mg/L (imipenem) ACI0118 s__Acinetobacter baumannii blaOXA-97 blaOXA-97 WP_063864544.1 - - ARO:3001647 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 18299404 ECO:0001103 natural variation mutant evidence strong MIC 32 mg/L (imipenem) ; MIC 16 mg/L (meropenem) ACI0119 s__Acinetobacter baumannii blaOXA-97 blaOXA-97 WP_063864544.1 - - ARO:3001647 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 18299404 ECO:0001103 natural variation mutant evidence strong MIC 32 mg/L (imipenem) ; MIC 16 mg/L (meropenem) ACI0120 s__Acinetobacter baumannii blaOXA-164 blaOXA-164 WP_063861121.1 - - ARO:3001662 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 20921306 ECO:0001103 natural variation mutant evidence strong MIC 8...>=16 mg/L (imipenem) ; MIC 2...8 mg/L (meropenem) (Vitek2) ; MIC 32 mg/L (imipenem) ; MIC 8...32 mg/L (meropenem) (Etest) ACI0121 s__Acinetobacter baumannii blaOXA-164 blaOXA-164 WP_063861121.1 - - ARO:3001662 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 20921306 ECO:0001103 natural variation mutant evidence strong MIC 8...>=16 mg/L (imipenem) ; MIC 2...8 mg/L (meropenem) (Vitek2) ; MIC 32 mg/L (imipenem) ; MIC 8...32 mg/L (meropenem) (Etest) ACI0122 s__Acinetobacter baumannii blaOXA-235 blaOXA-235 WP_000854009.1 - - ARO:3001676 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (imipenem) ACI0123 s__Acinetobacter baumannii blaOXA-235 blaOXA-235 WP_000854009.1 - - ARO:3001676 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (meropenem) ACI0124 s__Acinetobacter baumannii blaOXA-236 blaOXA-236 WP_063862170.1 - - ARO:3001677 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (imipenem) ACI0125 s__Acinetobacter baumannii blaOXA-236 blaOXA-236 WP_063862170.1 - - ARO:3001677 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (meropenem) ACI0126 s__Acinetobacter baumannii blaOXA-237 blaOXA-237 WP_000854010.1 - - ARO:3001678 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (imipenem) ACI0127 s__Acinetobacter baumannii blaOXA-237 blaOXA-237 WP_000854010.1 - - ARO:3001678 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 23439638 ECO:0001103 natural variation mutant evidence strong MIC >=16 mg/L (meropenem) ACI0128 s__Acinetobacter baumannii blaOXA-143_fam blaOXA-143_fam - - NF000464.2 ARO:3007701 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0129 s__Acinetobacter baumannii blaOXA-143_fam blaOXA-143_fam - - NF000464.2 ARO:3007701 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence strong Phenotype of this gene family inferred from MICs of several members. ACI0130 s__Acinetobacter baumannii blaOXA-143 blaOXA-143 WP_063861042.1 - - ARO:3001654 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 19770279 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ACI0131 s__Acinetobacter baumannii blaOXA-143 blaOXA-143 WP_063861042.1 - - ARO:3001654 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 19770279 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (meropenem) ACI0132 s__Acinetobacter baumannii blaOXA-182 blaOXA-182 WP_063861266.1 - - ARO:3001709 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 20884158 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected Phenotype of this gene in Acinetobacter baumannii inferred from the other members of the family. ACI0133 s__Acinetobacter baumannii blaOXA-182 blaOXA-182 WP_063861266.1 - - ARO:3001709 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 20884158 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected Phenotype of this gene in Acinetobacter baumannii inferred from the other members of the family. ACI0134 s__Acinetobacter baumannii blaOXA-231 blaOXA-231 WP_063862128.1 - - ARO:3001670 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) "22736746 24566181" ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ACI0135 s__Acinetobacter baumannii blaOXA-231 blaOXA-231 WP_063862128.1 - - ARO:3001670 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) "22736746 24566181" ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (meropenem) ACI0136 s__Acinetobacter baumannii blaOXA-253 blaOXA-253 WP_032495764.1 - - ARO:3001689 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 24566181 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ACI0137 s__Acinetobacter baumannii blaOXA-253 blaOXA-253 WP_032495764.1 - - ARO:3001689 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 24566181 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (meropenem) ACI0138 s__Acinetobacter baumannii blaNDM blaNDM - - NF000259.2 ARO:3000057 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected Phenotype of this gene family inferred from MICs of several members. ACI0139 s__Acinetobacter baumannii blaNDM blaNDM - - NF000259.2 ARO:3000057 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) - ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected Phenotype of this gene family inferred from MICs of several members. ACI0140 s__Acinetobacter baumannii blaNDM-1 blaNDM-1 WP_004201164.1 - - ARO:3000589 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 21693460 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ACI0141 s__Acinetobacter baumannii blaNDM-1 blaNDM-1 WP_004201164.1 - - ARO:3000589 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 21693460 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (meropenem) ACI0142 s__Acinetobacter baumannii blaNDM-2 blaNDM-2 WP_063860860.1 - - ARO:3000590 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 21427107 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ACI0143 s__Acinetobacter baumannii blaNDM-2 blaNDM-2 WP_063860860.1 - - ARO:3000590 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 21427107 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (meropenem) ACI0144 s__Acinetobacter baumannii blaNDM-6 blaNDM-6 WP_032495384.1 - - ARO:3002356 - Gene presence detected acquired imipenem - nonwildtype R MIC > 4 mg/L EUCAST v14.0 (2024) 33240245 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (imipenem) ACI0145 s__Acinetobacter baumannii blaNDM-6 blaNDM-6 WP_032495384.1 - - ARO:3002356 - Gene presence detected acquired meropenem - nonwildtype R MIC > 8 mg/L EUCAST v14.0 (2024) 33240245 ECO:0001103 natural variation mutant evidence strong MIC >32 mg/L (meropenem) ACI0146 s__Acinetobacter baumannii blaOXA-51_fam blaOXA-51_fam - - NF000268.2 ARO:3007725 - Gene presence detected core - carbapenem wildtype S not applicable EUCAST v15.0 (2025) 15649299 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "OXA-51-like are wt carbapenem-susceptible. OXA-51-like are not carbapenemases, with a few exceptions: carbapenem-resistance mediated through the OXA-51-like need two things; ISAba1 upstream, and a valine at position 167. This valine is found in OXA-82, OXA-107, OXA-113, and OXA-219. (also OXA-108,-115,-138,-174,-175,-176,-177,-194,-195,-195,-197,-219,-545)" ACI0147 s__Acinetobacter baumannii blaOXA-51_fam blaOXA-51_fam - - NF000268.2 ARO:3007725 c.-7ins[ISAba1:inv] Promoter variant detected acquired - carbapenem nonwildtype S not applicable EUCAST v15.0 (2025) "22717017, 23014718, 30124881" ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "OXA-51-like are wt carbapenem-susceptible. OXA-51-like are not carbapenemases, with a few exceptions: carbapenem-resistance mediated through the OXA-51-like need two things; ISAba1 upstream, and a valine at position 167. This valine is found in OXA-82, OXA-107, OXA-113, and OXA-219.(also OXA-108,-115,-138,-174,-175,-176,-177,-194,-195,-195,-197,-219,-545)" ACI0148 s__Acinetobacter baumannii blaOXA-51_fam blaOXA-51_fam - - NF000268.2 ARO:3007725 p.Leu167Val Protein variant detected acquired - carbapenem nonwildtype S not applicable EUCAST v15.0 (2025) "23014718, 35562886" "ECO:0001103 natural variation mutant evidence, ECO:0000005 enzymatic activity assay evidence" moderate lacks evidence of the degree to which MIC is affected "OXA-51-like are wt carbapenem-susceptible. OXA-51-like are not carbapenemases, with a few exceptions: carbapenem-resistance mediated through the OXA-51-like need two things; ISAba1 upstream, and a valine at position 167. This valine is found in OXA-82, OXA-107, OXA-113, and OXA-219.(also OXA-108,-115,-138,-174,-175,-176,-177,-194,-195,-195,-197,-219,-545)" ACI0149 s__Acinetobacter baumannii ACI0147 & ACI0148 - - - - - - Combination - - carbapenem nonwildtype R not applicable EUCAST v15.0 (2025) 23014718 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "OXA-51-like are wt carbapenem-susceptible. OXA-51-like are not carbapenemases, with a few exceptions: carbapenem-resistance mediated through the OXA-51-like need two things; ISAba1 upstream, and a valine at position 167. This valine is found in OXA-82, OXA-107, OXA-113, and OXA-219.(also OXA-108,-115,-138,-174,-175,-176,-177,-194,-195,-195,-197,-219,-545). In a chromosomal context, OXA-66 not preceded by ISAba1 increases the MIC of imipenem from 0.5 mg/L to 2 mg/L, and when OXA-66 is preceded by ISAba1 it increases the MIC of imipenem from 0.5 mg/L to 4 mg/L, in both cases not reaching the resitance level (PMID19307373)." ACI0150 s__Acinetobacter baumannii blaOXA-51 blaOXA-51 WP_002033109.1 - - ARO:3001612 - Gene presence detected core imipenem - wildtype S MIC <= 4 mg/L EUCAST v15.0 (2025) "15649299, 35562886" ECO:0001103 natural variation mutant evidence strong "The presence of OXA-51, OXA-66 or OXA-99 increases the MIC of imipenem from 0.125 mg/L to 1 mg/L (PMID 35562886)." ACI0151 s__Acinetobacter baumannii blaOXA-51 blaOXA-51 WP_002033109.1 - - ARO:3001612 - Gene presence detected core meropenem - wildtype S MIC <= 8 mg/L EUCAST v15.0 (2025) 15649299 ECO:0001103 natural variation mutant evidence strong ACI0152 s__Acinetobacter baumannii blaADC blaADC - - NF000425.2 ARO:3005459 - Gene presence detected core - third-generation cephalosporin wildtype R not applicable ECOFF (May 2025) 10639377 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "ADC is responsible for 3rd generation cephalosporin resistance: ceftazidime and cefotaxime. ISAba1, typically 9bp upstream, but they can be found also 7bp upstream, increase MICs." ACI0153 s__Acinetobacter baumannii blaADC blaADC - - NF000425.2 ARO:3005459 - Gene presence detected core ceftazidime - wildtype R MIC > 16 mg/L ECOFF (May 2025) 10639377 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "ADC is responsible for 3rd generation cephalosporin resistance: ceftazidime and cefotaxime. ISAba1, typically 9bp upstream, but they can be found also 7bp upstream, increase MICs." ACI0154 s__Acinetobacter baumannii blaADC blaADC - - NF000425.2 ARO:3005459 - Gene presence detected core cefotaxime - wildtype R MIC > 64 mg/L ECOFF (May 2025) 10639377 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "ADC is responsible for 3rd generation cephalosporin resistance: ceftazidime and cefotaxime. ISAba1, typically 9bp upstream, but they can be found also 7bp upstream, increase MICs." ACI0155 s__Acinetobacter baumannii blaADC-1 blaADC-1 WP_004714775.1 - - ARO:3003847 - Gene presence detected core - third-generation cephalosporin wildtype R not applicable ECOFF (May 2025) 10639377 ECO:0001103 natural variation mutant evidence moderate lacks evidence of the degree to which MIC is affected "ADC is responsible for 3rd generation cephalosporin resistance: ceftazidime and cefotaxime. ISAba1, typically 9bp upstream, but they can be found also 7bp upstream, increase MICs." ACI0156 s__Acinetobacter baumannii blaADC-1 blaADC-1 WP_004714775.1 - - ARO:3003847 - Gene presence detected core ceftazidime - wildtype R MIC > 16 mg/L ECOFF (May 2025) 10639377 "ECO:0001103 natural variation mutant evidence, ECO:0005027 genetic transformation evidence, ECO:0000005 enzymatic activity assay evidence" moderate lacks evidence of the degree to which MIC is affected The presence of this variant increased the MIC from <=0.125 mg/L to 16 mg/L in an E. coli background (PMID 10639377). ACI0157 s__Acinetobacter baumannii blaADC-1 blaADC-1 WP_004714775.1 - - ARO:3003847 - Gene presence detected core cefotaxime - wildtype R MIC > 64 mg/L ECOFF (May 2025) 10639377 "ECO:0001103 natural variation mutant evidence, ECO:0005027 genetic transformation evidence, ECO:0000005 enzymatic activity assay evidence" moderate lacks evidence of the degree to which MIC is affected The presence of this variant increased the MIC from <=0.125 mg/L to 4 mg/L in an E. coli background (PMID 10639377). ACI0158 s__Acinetobacter baumannii ant(3'')-II ant(3'')-II - - NF033220.1 ARO:3004089 - Gene presence detected core gentamicin - wildtype S not applicable EUCAST v15.0 (2025) 28152054 ECO:0001103 natural variation mutant evidence strong AMG's: ant(3'')-IIa and ant(3'')-IIc are intrinsic (>99% of genomes). These enzymes confer resistance only to spectinomycin and streptomycin. See rules ACI0166 and ACI0167. ACI0159 s__Acinetobacter baumannii ant(3'')-II ant(3'')-II - - NF033220.1 ARO:3004089 - Gene presence detected core tobramycin - wildtype S not applicable EUCAST v15.0 (2025) 28152054 ECO:0001103 natural variation mutant evidence strong AMG's: ant(3'')-IIa and ant(3'')-IIc are intrinsic (>99% of genomes). These enzymes confer resistance only to spectinomycin and streptomycin. See rules ACI0166 and ACI0167. ACI0160 s__Acinetobacter baumannii amvA amvA WP_001170306.1 - - - - Gene presence detected core - - wildtype S not applicable - 34552198 - - lacks clinical evidence Core gene encoding a�spermidine and spermine efflux pump (PMID: 34552198). Relevance to antimicrobials lacks evidence. ACI0161 s__Acinetobacter baumannii gyrA - WP_000116450.1 - - ARO:3003292 - Gene presence detected core - fluoroquinolone antibiotic wildtype S not applicable EUCAST v15.0 (2025) 7625818 ECO:0001103 natural variation mutant evidence strong "Fluoroquinolone resistance: FQ-R is mediated by amino acid substitutions in GyrA and ParC, the vast majority of FQ-R isolates have the following substitutions, S81L and S84L, in GyrA and ParC respectively. There are a few other substitutions in the literature. Be aware, that earlier publications used E. coli numbering for GyrA/ParC. Nowadays we don’t use the E. coli numbering. wild type GyrA isolates are susceptible to FQ's" ACI0162 s__Acinetobacter baumannii gyrA - WP_000116450.1 - - ARO:3003292 p.Ser81Leu Protein variant detected acquired - fluoroquinolone antibiotic nonwildtype R not applicable EUCAST v15.0 (2025) 7625818 ECO:0001103 natural variation mutant evidence strong "Fluoroquinolone resistance: FQ-R is mediated by amino acid substitutions in GyrA and ParC, the vast majority of FQ-R isolates have the following substitutions, S81L and S84L, in GyrA and ParC respectively. There are a few other substitutions in the literature. Be aware, that earlier publications used E. coli numbering for GyrA/ParC. Nowadays we don’t use the E. coli numbering. Ser81-Leu GyrA isolates are resistant to FQ's with ciprofloxacin MICs raised to 4mg/L" ACI0163 s__Acinetobacter baumannii parC - WP_000116450.1 - - ARO:3003292 - Gene presence detected core - fluoroquinolone antibiotic wildtype S not applicable EUCAST v15.0 (2025) 9222045 ECO:0001103 natural variation mutant evidence strong The ParC substituion is nearly always associated with the GyrA FQ-R substitutions ACI0164 s__Acinetobacter baumannii parC - WP_000116450.1 - - ARO:3003292 p.Ser84Leu Protein variant detected acquired - fluoroquinolone antibiotic nonwildtype R not applicable EUCAST v15.0 (2025) 36010006 ECO:0001103 natural variation mutant evidence strong The ParC substituion is nearly always associated with the GyrA FQ-R substitutions ACI0165 s__Acinetobacter baumannii ant(3'')-II ant(3'')-II - - NF033220.1 ARO:3004089 - Gene presence detected core amikacin - wildtype S not applicable EUCAST v15.0 (2025) 28152054 ECO:0001103 natural variation mutant evidence strong AMG's: ant(3'')-IIa and ant(3'')-IIc are intrinsic (>99% of genomes). These enzymes confer resistance only to spectinomycin and streptomycin. See rules ACI0166 and ACI0167. "PGH, MH,BL,VB" ACI0166 s__Acinetobacter baumannii ant(3'')-II ant(3'')-II - - NF033220.1 ARO:3004089 - Gene presence detected core spectinomycin - wildtype R not applicable EUCAST v15.0 (2025) 28152054 ECO:0001103 natural variation mutant evidence strong AMG's: ant(3'')-IIa and ant(3'')-IIc are intrinsic (>99% of genomes). These enzymes confer resistance only to spectinomycin and streptomycin. "PGH, MH,BL,VB" ACI0167 s__Acinetobacter baumannii ant(3'')-II ant(3'')-II - - NF033220.1 ARO:3004089 - Gene presence detected core streptomycin - wildtype R not applicable EUCAST v15.0 (2025) 28152054 ECO:0001103 natural variation mutant evidence strong AMG's: ant(3'')-IIa and ant(3'')-IIc are intrinsic (>99% of genomes). These enzymes confer resistance only to spectinomycin and streptomycin. "PGH, MH" ACI0168 s__Acinetobacter baumannii abaF abaF ABO11759.2 - - - Gene presence detected core fosfomycin - wildtype R not applicable EUCAST Expected Resistant Phenotypes v1.2 (2023) 27650185 ECO:0000012 functional complementation evidence; ECO:00001091 knockout phenotypic evidence strong low clinical relevance AbaF is an MFS efflux pump. Gene knockout in A. baumannii revealed its contribution to fosfomycin resistance.